11/23/2016: US patent was issued after a multi year saga. The research started more than 10 years ago and resulted in certain claims being granted in 2012. However the patent office examiner did not allow all claims, specifically the direct intra articular injection of these dyes that are found in plants. So more time and money was spent and now the issue is settled.
US 9, 486, 468 B2 was issued November 8, 2016 granting claims stating that intra articular of anthocyanins and or anthocyanidins to stimulate the synovium (joint lining) to make a growth hormone; IGF-1. The result there in will improve the nutrition and protect the cartilage in the joint and potentially heal the arthritic joint.
The sage is not over yet in that subsequent research showed that the active ingredient is the primary metabolite of those dyes; protocatechuic acid (PCA). I now have supporting research to expand the claims to include the injection of PCA. So back to the patent office with more money and time.
These are just the first of many hurdles, as I now face the FDA reglations before available for marketing.