What am I up to?

“Not always this laid back”

“Not always this laid back”

Thank you for asking. I am asked this question so often. This phase may just be a salutation, but I have learned many have a curiosity about my various endeavors. A blog seemed like the best way to answer this question on a regular basis. In addition, this blog provides a means for me to keep track in an organized fashion of what I am up to.

The purpose is to record and relate what I am up to these days. The information will be in one place for recording memoirs and historical events. It will be a place to document the present and consider the future.
I expect to regularly make entries concerning various categories: physician/surgeon; medical research and development; the golf adventures and Life. You may see a recent post or follow the topic that might interest you.

Let me know what you think as this blog will becomes my “Lectronic Legacy” in what ever time remains.

Physician/Surgeon

“30 years at the bedside” circa 1980

“30 years at the bedside” circa 1980

In the course of my practice I was one of the pioneers in arthroscopic surgery. This resulted in hundreds of surgeon visitors, such that Ingham Medical Center in Lansing created the first operating room dedicated to arthroscopic surgery including a glass wall for visitors to comfortably observe surgery.

Arthroscopic Suite Ingham Medical Center

Arthroscopic Suite Ingham Medical Center

First and foremost I am a physician/surgeon. No matter a physician’s special interest, the medical license says physician/surgeon. In the course of my medical practice, medicine became very specialized, me included. I went from medical doctor, to board certified orthopedic surgeon to arthroscopic surgeon. My business card indicated such. I did not go so far as to do only left knees and right elbows. When I saw this unfolding, I changed my business card my roots, a “new” specialty called Physician/Surgeon.

 

 

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Inventions/Patents

Inventions/Patents

Official Patent Document

Official Patent Document

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Golf

My friend and partner on the PGA Tour; Howard Twitty

My friend and partner on the PGA Tour; Howard Twitty

I started golf at age 11 a Burroughs Farms, a family recreational area for employees of Burroughs Adding Machine Company. This facility is now called Oak Pointe, west of Brighton, MI. I played on Royal Oak High School team which won the Michigan State High School Championship in 1951 (not a misprint on year). My last year at Michigan State and sfter I was admitted to medical school, I played #3 man on Michigan State College (at that time) golf team. My best competitive score was two under 70 against Notre Dame. I have enjoyed 3 holes in one, the longest being 265 yards in 1955. I played a few local country club invitationals over the years, winning once at the Lansing Country club with Otto Schubel.

Long hiatus in golf due to medical school and practice, but in 2002, I slipped on the ice after a Michigan State basketball game and dislocated my shoulder. This resulted in rotator cuff repair and exploring one handed putting. This led to interest in putting and putter design. This led to meeting Howard Twitty, former PGA tour player and the rest is history and daily documentation of new events now reflected in this blog’s “What are you up to in Golf”

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Life & life

Open Bible

Open Bible

These are musings about Life and life. Notice the capital letter on the first Life. The reason is that it is a synonym or code name for the person of Jesus Christ of Nazareth. He called himself the Way, The Truth and the Life. Over the years I have lived an imperfect life (not capitalized) which is one of the qualifications for becoming and remaining a Christian. There is a fun scripture that rhetorically says, “Does a well man need a doctor?” Only those with faults need apply.

I have written a number of manuscripts about Life and life. One such many people Christian or not have appreciated is my insight to what goes on in the operating room which resulted in a prayer for those undergoing surgery. (use the form to the right to sign up and get this free)

I have written a short manuscript on “A Physician Looks at Scriptural Healing”. Being a medical doctor and a Christian it was of interest to me, what the Bible recorded about healing. So it was important to me to make this study in light of my clinical experiences. I want the proceeds from this to go directly to Fresh Wind Christian Community in Benzie County, MI.

This section will have many other reflections on Life and life as we go along.

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Answering the frequently asked question (FAQ) of what am I up to now?

A BLOG seemed the best and most efficient means of answering the FAQs on a regular basis.  It might be said that I wear multiple hats or have many interests.  Discovery in medicine will always be the main topic.  However there are other categories; Golf Adventures, Inventions, and some Christian writings.  Hopefully the BLOG will be a format to tell what I am up to in each of these main endeavors.  It seems almost daily there are interesting events; at least to me. Perhaps the events may be of interest to others.

I want to make it clear, I am not retired.  Retirement it is bad for one’s health.  I concluded my clinical practice in 1995, but work regularly in these various endeavors.  I do not see anywhere in the Bible where retirement is to be desired or realized.  I have told my daughters that I will not be speaking at my retirement party.

From time to time I will answer publicly herein those questions that recently surfaced and may be of general interest.  I will not be recording what I had on my hot dog at a ball game, let alone focus on mundane events.

I trust I will accomplish the intended goal of answering “What am I up to?”

Another US Patent

5/31/2018: On May 29, 2018 I was issued US patent 9,982,963 B2

A firearm having tactile biofeedback reference feature.

It is based upon the same human response to sensation in the skin that was present in the grooved grip and the real feel gloves. It allows the person to shoot more accurately.

Expanded US patent for Arthritis joint injection

5/24/2018: Just learned that on June 5, 2018, U.S. Patent No. 9,987,296 will be published.

It is a continuation of a prior more general patent for intra articular injection to treat arthritis. This patent expanded the use of the common plant dye, Cyanidin-3-glucoside to include dextrose and addition of insulin or other growth hormones as well as slow release biodegradable vehicle.

Allowed Claims
1. A method of inhibiting interleukin-1 (IL-1) induced glycosaminoglycoside (GAG) release in an arthritic joint of a subject, comprising administering into the arthritic joint of the subject by an intra-articular injection, a composition comprising cyanidin-3-glucoside (C3G), glucose and a pharmaceutically acceptable carrier, wherein the concentration of glucose is about 5%, and wherein the C3G is administered at a dose of 0.002 mg to 100 mg per joint that is effective to elicit the inhibition of IL-1 induced GAG release in the arthritic joint of the subject.

2-3. (Cancelled)

4. The method according to claim 1, wherein the composition increases expression of IGF-1 in the arthritic joint.

5. The method according to claim 4, wherein the composition is provided in a biodegradable microsphere.

6. The method according to claim 5, wherein the biodegradable microsphere comprises a slow release bioabsorbable material.

7. The method according to claim 6, wherein the bioadsorbable material is 50/50 D, L lactide/glycolide or 85/15 D, L lactide/glycolide.

8. (Cancelled)

9. The method according to claim 1, wherein the composition has a chondroprotective and/or chondronutritive effect in the joint of a subject.

10. (Cancelled)

11. The method of claim 1, wherein the composition treats damaged cartilage in the arthritic joint.

12-15. (Cancelled)

16. The method of claim 1, wherein the joint is a synovial joint.

17. The method of claim 11, wherein the injection comprises the formation of anthocyanin metabolites in the synovial fluid.

18. The method according to claim 1, wherein the dose of 0.002 mg to 100 mg per joint of C3G is provided at a concentration not exceeding about 100 µM.

19. The method according to claim 1, wherein the composition is administered with IGF-1, insulin, or a mixture thereof.

20. A method for treating damaged cartilage in an arthritic joint in a subject, comprising administering into the arthritic joint of the subject, by an intra-articular injection, a composition that is a solution comprising an anthocyanin, glucose and a pharmaceutically acceptable carrier, wherein the concentration of the glucose is about 0.5% to about 10%;
wherein the anthocyanin is cyanidin-3-glucoside (C3G), and wherein the C3G is administered at a dose of 0.002 mg to 100 mg per joint.

21. The method according to claim 20, wherein the composition increases production of insulin-like growth factor-1 (IGF-1) in the joint.

22. The method according to claim 20, wherein the glucose is administered at about 5%.

23. The method according to claim 20, wherein the glucose is administered at about 10%.

Another US patent granted

5/24/2018: The background is important in appreciating the value of this patent.
Before antibiotics, bacteria were free floating in the body as individual bacteria.
There response to anti biotics was to mutate and or form colonies covered with a protective coating of a biofilm that the antibiotic could not penetrate. A total joint implant becomes infected when the first step the bacteria do is to produce a biofilm on the implant and from there, they grow the covered colony.

This US patent is important in that the solution applied to a total joint implant blocks the attachment of a biofilm and therefor the bacteria remain vulnerable to the protocatechuic acid (PCA) which destroys the biofilm and the bacteria.

This patent also provides a means to coat bandages in the manufacturing process. The PCA dries. When applied to a moist wound, the PCA is activated and kills the bacteria and causes would healing acceleration.

Allowed Claims

1. A method of reducing growth or development of a biofilm on a surface, comprising: contacting the surface with a composition comprising about 10% to about 50% of an anthocyanin metabolite or an anthocyanidin metabolite selected from protocatechuic acid and 2,4,6-trihydroxybenzaldehyde and mixtures and combinations thereof, wherein the contacting step reduces an initial attachment of a biofilm or a biofilm forming microorganism to the surface, thereby reducing the growth or development of the biofilm on the surface.
2. The method of claim 1, wherein the biofilm forming microorganism is selected from a Pseudomonas aeruginosa and a Methicillin-resistant Staphylococcus aureus.
3. The method of claim 1, wherein the composition is selected from a liquid, a sanitizer, a disinfectant, a swab, a salve, soap, foam, cream, solution, gel, spray, powder, crystals, antibacterial treatments, wipes, a lotion and combinations thereof.
4. The method of claim 1, wherein the surface is selected from a solid surface, a smooth surface, a porous or semi-porous surface, and a cloth-like surface.
5. The method of claim 1, wherein the surface is on an implant, a bandage, a catheter, a dressing, a heart or vascular grafts, or a wound.
6. The method of claim 1, wherein the surface is a ceramic surface.
7. The method of claim 1, wherein the contacting step is selected from wiping the surface, spraying the surface, soaking the surface, imbedding crystals of the anthocyanin metabolite or an anthocyanidin metabolite on or in the surface, or applying a bandage or wound dressing impregnated with the composition to the surface.
8. The method of claim 1, wherein the anthocyanin metabolite or an anthocyanidin metabolite is present in an amount of from about 10% to about 40% by weight of the composition.
9. The method of claim 1, wherein the anthocyanin metabolite or an anthocyanidin metabolite is present in an amount of from about 20% to about 30% by weight of the composition.
10. The method of claim 1, wherein the anthocyanin metabolite or an anthocyanidin metabolite is protocatechuic acid.
11. The method of claim 1, wherein the surface is contacted with the composition for up to two years.
12. The method of claim 3, wherein the composition comprises protocatechuic acid or 2,4,6–trihydroxybenzaldehyde or a mixture or combination thereof dissolved in a solution.
13. The method of claim 12, wherein the solution further comprises a carrier.
14. The method of claim 13, wherein the carrier is selected from water, isopropyl alcohol, and ethyl alcohol.
15. The method of claim 14, wherein the isopropyl alcohol is present at a concentration of about 70% to about 91%.
16. The method of claim 14, wherein the solution comprises 10% to 30% protocatechuic acid dissolved in about 70% isopropyl alcohol.

Skin health patent issued

4/11/2018: The US Patent office issued # 9,925,152 B2 on March 27, 2018. This was a continuation of the parent patent 9,498,413 which claimed protocatechuic acid as a broad spectrum antibiotic and a wound healing accelerator.

The additional claims indicated the collagen formation properties and potential to reduce scar formation. The clinical application may accompany cosmetic exfoliation and surgical dermabrasion yielding a form of skin wrinkle treatment.

See these granted claims.

10. The method of claim 1 wherein the treating of the wound is a cosmetic method of treating skin to enhance skin healing, wherein the composition is administered topically, orally or by intradermal or subcutaneous injection to a skin tissue, wherein the composition promotes an effect selected from the group consisting of reducing inflammation, optimizing growth hormone production, and increasing collagen stimulation.

11. The method according to claim 1, wherein said administration further results in reduced scar formation.

Glove patent granted

4/4/2018: The US patent 9,918,504 was granted on March 20, 2018 for the Real Feel Glove.

Deception does not always require a lie

4/2/2018: There can be a deception without there being a lie. The best example I know of is the following. A person may say that god spoke to them to take a certain action. It could be true, but they need to know what god was speaking. For instance the devil is the god of this world. He is legitimately so. (2 Corinthians 4:4) One of his roles is to deceive.

Therefore, it is not a lie if the devil delivers a message indicating it is god speaking. It is a spiritual impression, but not the Holy Spirit, the God of the Universe, the Lord of Hosts or Jesus.

This is commonly seen when a person murders their family and says god told them to do it. It was the god of this world, the devil. It does not match the Word of God that says not to murder.

So what ever we believe we hear from god, must match the Word of the one True God. There will be a biblical match. Also, we must use the Spirit of Discernment to consistently do the right thing.

Another US Patent granted

3/31/2018: I was recently granted the following US patent.


9,925,152 Antimicrobials and methods of use thereof for wound healing. March 27, 2018.
This was a continuation of the parent application that adds 2,4,6 trihydroxybenzaldehyde to the broad spectrum antibiotic, plus collagen proliferation (i.e. wrinkle treatment) and reduction in scar formation.