Currently browsing: Inventions/Patents

Food Supplement Cautions

10/25/2018:  There are published cautions about a number of food substances. www.consumerreports.org/vitamins-supplements/15-supplement-ingredients-to-always-avoid/ I have been very cautions as I have explored the health benefits of food supplements.  I have done extensive testing and review of the literature on the food metabolite I am using; protocatechuic acid.  It is safe.  The FDA considers it Generally Recognized As Safe (GRAS) as a food additive for flavoring. My first launch is www.4WhatAilsU.com   This is an antioxidant pill.  The web site has all the information.

Another US Patent issued

10/4/2018:  I learned today that another US Patent issued: 10,077,967 on September 18, 2018.  This is a tape to be attached to equipment, especially a sports handle.  The tape has either a thin longitudinal groove or elevation that makes an impression on the holder’s skin.  This impression allows the holder to have better orientation of the handle.  It is based upon the psychomotor principle know as “tactile edge orientation processing”.  This is fancy wording that means the human can reach into their pocket and discern without looking by feeling the difference between a coin and a key by way of feeling the edge of each. The function in sports is the same principle as the groove golf grip and the glove with holes in the finger tips work.  The player has a better sense of orientation and there for proprioception to be more accurate with performance. PTL

Web Site Launch: www.4WhatAilsU.com

9/15/2018:  I launched www.4WhatAilsU.com this past week on the PGA Champions Tour.  It is offering a Powerful Broad Spectrum anti-oxidant. It is a natural food substance; the metabolite from the dyes that make blueberries blue and cherries red. I had amazing good response and immediate results from first adopters, especially the tour player’s caddies.  

Another US Patent

5/31/2018: On May 29, 2018 I was issued US patent 9,982,963 B2 A firearm having tactile biofeedback reference feature. It is based upon the same human response to sensation in the skin that was present in the grooved grip and the real feel gloves. It allows the person to shoot more accurately.

Expanded US patent for Arthritis joint injection

5/24/2018: Just learned that on June 5, 2018, U.S. Patent No. 9,987,296 will be published. It is a continuation of a prior more general patent for intra articular injection to treat arthritis. This patent expanded the use of the common plant dye, Cyanidin-3-glucoside to include dextrose and addition of insulin or other growth hormones as well as slow release biodegradable vehicle. Allowed Claims 1. A method of inhibiting interleukin-1 (IL-1) induced glycosaminoglycoside (GAG) release in an arthritic joint of a subject, comprising administering into the arthritic joint of the subject by an intra-articular injection, a composition comprising cyanidin-3-glucoside (C3G), glucose and a pharmaceutically acceptable carrier, wherein the concentration of glucose is about 5%, and wherein the C3G is administered at a dose of 0.002 mg to 100 mg per joint that is effective to elicit the inhibition of IL-1 induced GAG release in the arthritic joint of the subject. 2-3. (Cancelled) 4. The method according to claim 1, wherein the composition increases expression of IGF-1 in the arthritic joint. 5. The method according to claim 4, wherein the composition is provided in a biodegradable microsphere. 6. The method according to claim 5, wherein the biodegradable microsphere comprises a slow release bioabsorbable material. 7. The method according to claim 6, wherein the bioadsorbable material is 50/50 D, L lactide/glycolide or 85/15 D, L lactide/glycolide. 8. (Cancelled) 9. The method according to claim 1, wherein the composition has a chondroprotective and/or chondronutritive effect in the joint of a subject. 10. (Cancelled) 11. The method of claim 1, wherein the composition treats damaged cartilage in the arthritic joint. 12-15. (Cancelled) 16. The method of claim 1, wherein the joint is a synovial joint. 17. The method of claim 11, wherein the injection comprises the formation of anthocyanin metabolites in the synovial fluid. 18. The method according to claim 1, wherein the dose of 0.002 mg to 100 mg per joint of C3G is provided at a concentration not exceeding about 100 µM. 19. The method according to claim 1, wherein the composition is administered with IGF-1, insulin, or a mixture thereof. 20. A method for treating damaged cartilage in an arthritic joint in a subject, comprising administering into the arthritic joint of the subject, by an intra-articular injection, a composition that is a solution comprising an anthocyanin, glucose and a pharmaceutically acceptable carrier, wherein the concentration of the glucose is about 0.5% to about 10%; wherein the anthocyanin is cyanidin-3-glucoside (C3G), and wherein the C3G is administered at a dose of 0.002 mg to 100 mg per joint. 21. The method according to claim 20, wherein the composition increases production of insulin-like growth factor-1 (IGF-1) in the joint. 22. The method according to claim 20, wherein the glucose is administered at about 5%. 23. The method according to claim 20, wherein the glucose is administered at about 10%.

Another US patent granted

5/24/2018: The background is important in appreciating the value of this patent. Before antibiotics, bacteria were free floating in the body as individual bacteria. There response to anti biotics was to mutate and or form colonies covered with a protective coating of a biofilm that the antibiotic could not penetrate. A total joint implant becomes infected when the first step the bacteria do is to produce a biofilm on the implant and from there, they grow the covered colony. This US patent is important in that the solution applied to a total joint implant blocks the attachment of a biofilm and therefor the bacteria remain vulnerable to the protocatechuic acid (PCA) which destroys the biofilm and the bacteria. This patent also provides a means to coat bandages in the manufacturing process. The PCA dries. When applied to a moist wound, the PCA is activated and kills the bacteria and causes would healing acceleration. Allowed Claims 1. A method of reducing growth or development of a biofilm on a surface, comprising: contacting the surface with a composition comprising about 10% to about 50% of an anthocyanin metabolite or an anthocyanidin metabolite selected from protocatechuic acid and 2,4,6-trihydroxybenzaldehyde and mixtures and combinations thereof, wherein the contacting step reduces an initial attachment of a biofilm or a biofilm forming microorganism to the surface, thereby reducing the growth or development of the biofilm on the surface. 2. The method of claim 1, wherein the biofilm forming microorganism is selected from a Pseudomonas aeruginosa and a Methicillin-resistant Staphylococcus aureus. 3. The method of claim 1, wherein the composition is selected from a liquid, a sanitizer, a disinfectant, a swab, a salve, soap, foam, cream, solution, gel, spray, powder, crystals, antibacterial treatments, wipes, a lotion and combinations thereof. 4. The method of claim 1, wherein the surface is selected from a solid surface, a smooth surface, a porous or semi-porous surface, and a cloth-like surface. 5. The method of claim 1, wherein the surface is on an implant, a bandage, a catheter, a dressing, a heart or vascular grafts, or a wound. 6. The method of claim 1, wherein the surface is a ceramic surface. 7. The method of claim 1, wherein the contacting step is selected from wiping the surface, spraying the surface, soaking the surface, imbedding crystals of the anthocyanin metabolite or an anthocyanidin metabolite on or in the surface, or applying a bandage or wound dressing impregnated with the composition to the surface. 8. The method of claim 1, wherein the anthocyanin metabolite or an anthocyanidin metabolite is present in an amount of from about 10% to about 40% by weight of the composition. 9. The method of claim 1, wherein the anthocyanin metabolite or an anthocyanidin metabolite is present in an amount of from about 20% to about 30% by weight of the composition. 10. The method of claim 1, wherein the anthocyanin metabolite or an anthocyanidin metabolite is protocatechuic acid. 11. The method of claim 1, wherein the surface is contacted with the composition for up to two years. 12. The method of claim 3, wherein the composition comprises protocatechuic acid or 2,4,6–trihydroxybenzaldehyde or a mixture or combination thereof dissolved in a solution. 13. The method of claim 12, wherein the solution further comprises a carrier. 14. The method of claim 13, wherein the carrier is selected from water, isopropyl alcohol, and ethyl alcohol. 15. The method of claim 14, wherein the isopropyl alcohol is present at a concentration of about 70% to about 91%. 16. The method of claim 14, wherein the solution comprises 10% to 30% protocatechuic acid dissolved in about 70% isopropyl alcohol.

Skin health patent issued

4/11/2018: The US Patent office issued # 9,925,152 B2 on March 27, 2018. This was a continuation of the parent patent 9,498,413 which claimed protocatechuic acid as a broad spectrum antibiotic and a wound healing accelerator. The additional claims indicated the collagen formation properties and potential to reduce scar formation. The clinical application may accompany cosmetic exfoliation and surgical dermabrasion yielding a form of skin wrinkle treatment. See these granted claims. 10. The method of claim 1 wherein the treating of the wound is a cosmetic method of treating skin to enhance skin healing, wherein the composition is administered topically, orally or by intradermal or subcutaneous injection to a skin tissue, wherein the composition promotes an effect selected from the group consisting of reducing inflammation, optimizing growth hormone production, and increasing collagen stimulation. 11. The method according to claim 1, wherein said administration further results in reduced scar formation.